| Articles
Index-Integrated Healthcare |
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| Patrick Quanten MD Independent
Health Adviser |
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| Lipid Regulating Drugs |
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| Anion-exchange resins: |
Clestyramine,
colestipol
They interfere with the absorption of fat-soluble vitamins.
They cause gastrointestinal side-effects, such as constipation,
but also diarrhoea,
as well as nausea, vomiting and abdominal pain. An increased
bleeding tendency has been reported too.
The risk of drug interference with all other medication is
very high.
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| Fibrates: |
Clofibrate,
bezafibrate, ciprofibrate, fenofibrate, gemfibrozil
All can cause muscle inflammation.
Other problems mentioned are severe kidney and liver impairment,
which can lead to biliary cirrhosis, gallbladder disease.
Side-effects include gastrointestinal symptoms, itching, skin
eruptions, impotence, headache, dizziness, fatigue, hair loss,
anaemia, pancreatitis, heart fibrillation. |
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| Statins: |
| Atorvastatin,
cerivastatin, fluvastatin, pravastatin, simvastatin Liver
tests should be carried out before and within 1 - 3 months
of starting treatment and thereafter at intervals of 6 months
for 1 year, unless indicated sooner by symptoms or signs suggestive
of liver toxicity. Patients should also be advised to report
unexplained muscle pain. Muscle inflammation is more frequently
seen with combined treatment protocols including fibrates,
nicotinic acid and immunosuppressants such as cyclosporine
or methotrexate. Further side-effects include headache, abdominal
pain, flatulence, diarrhoea, nausea and vomiting. |
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| Nicotinic acid: |
| Acipimox,
nicotinic acid These cause peptic ulcers, vasodilatation,
flushing, itching, rashes, heartburn, epigastric pain, nausea,
diarrhoea, headache, malaise, dry eyes, bronchospasm, anaphylactic
shock. |
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| All the above
information comes from the pharmaceutical industry and is
supplied to all doctors. But there is an awful lot more known
about the cholesterol lowering drugs. |
| 1. |
In
a study published in the Journal of the American Medical
Association (JAMA), Thomas B. Newman MD, MPH and co-workers
show that all cholesterol-lowering drugs, both the early
drugs known as fibrates (clofibrate, gemfibrozil) and
the newer drugs known as statins (Lipitor, Pravachol,
Zocor), cause cancer in rodents at the equivalent doses
used by man. |
| 2. |
Evidence
from the cholesterol-lowering drug trial known as CARE
(Cholesterol And Recurrent Events) showed that Pravachol™
reduced the chance of suffering from a heart attack
by an absolute reduction rate of 1.1%. This miniscule
benefit was accompanied by a 1500% increase in breast
cancer among women taking Pravachol. An increase in
cancer rates among Pravachol users was also shown in
the drug trial known as PROSPER. |
| 3. |
It
is rare that cancer would show up in most other cholesterol-lowering
drug trials. Drug company-funded studies for these drugs
are conveniently short in nature, typically 5 years
or less. It can take decades for cancer to develop.
Therefore, cancer rarely shows up. In fact, even heavy
smoking will not cause lung cancer within 5 years. Yet
it is a well-known fact that smoking leads to lung cancer.
Therefore, as long as statin drug trials last only 5
years, this side effect will continue to fly below the
radar. |
| 4. |
Dr.
Gloria Troendle, deputy director for the Division of
Metabolism and Endocrine Drug Products for the FDA (Food
and Drug Administration - USA), noted that the cholesterol-lowering
drug gemfibrozil belonged to a class of drugs that has
repeatedly been shown to increase death rates among
users. |
| 5. |
Published
in Nature Medicine, Dr. Michael Simons of Beth Israel
Deaconess Medical Center in Boston shows that statin
drugs mimic a substance known as vascular endothelial
growth factors (VEGF). The biochemical VEGF promotes
the growth of new blood vessels. This benefit is quickly
negated by the potential for growth of cancer. The British
Journal of Cancer reports that VEGF plays an important
role in the spread of colorectal (bowel) cancer. Further,
for those who already have tumours, VEGF and compounds
that mimic VEGF significantly diminish that person's
survival time. |
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| The story of
the "cholesterol" disease is a non-entity. There is no cholesterol
disease, only toxicity. And furthermore, the treatment for
the non-existing disease creates a variety of extremely serious
health problems. |
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An example of modern times!
© By Patrick Quanten MD |
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